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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAN3
All Species:
23.33
Human Site:
T217
Identified Species:
34.22
UniProt:
Q58A45
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q58A45
NP_787050.4
741
82181
T217
A
P
R
R
R
S
H
T
P
N
P
A
S
Y
M
Chimpanzee
Pan troglodytes
XP_001136622
741
82148
T217
A
P
R
R
R
S
H
T
P
N
P
A
S
Y
M
Rhesus Macaque
Macaca mulatta
XP_001097210
741
82134
T217
A
P
R
R
R
S
H
T
P
N
P
A
S
Y
M
Dog
Lupus familis
XP_543150
987
105833
T463
A
P
R
R
R
S
H
T
P
N
P
A
N
Y
M
Cat
Felis silvestris
Mouse
Mus musculus
Q640Q5
691
76362
F204
T
V
G
G
T
T
Y
F
Y
T
D
T
T
P
A
Rat
Rattus norvegicus
XP_002724835
883
95283
T359
A
P
R
R
R
S
H
T
P
N
P
A
S
F
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519591
717
78728
G221
V
T
Q
A
P
S
P
G
Q
V
I
Q
K
E
T
Chicken
Gallus gallus
XP_417120
757
83269
T234
A
P
R
R
R
S
H
T
P
N
P
A
N
Y
M
Frog
Xenopus laevis
NP_001128699
631
68072
N144
R
M
Q
Q
R
M
T
N
S
S
S
S
P
S
L
Zebra Danio
Brachydanio rerio
XP_002666687
799
86684
R276
H
T
S
P
A
P
R
R
R
S
H
T
P
N
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728797
788
85176
R221
A
Q
T
P
L
K
G
R
G
A
M
M
R
Q
E
Honey Bee
Apis mellifera
XP_623553
607
67474
Q120
I
G
N
V
G
A
S
Q
I
G
Y
V
Y
P
G
Nematode Worm
Caenorhab. elegans
P34653
632
71182
Y145
E
N
R
G
G
T
T
Y
F
Y
T
E
P
T
E
Sea Urchin
Strong. purpuratus
XP_796055
760
83393
R236
T
S
R
K
E
F
R
R
A
Q
A
P
S
A
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36102
679
76436
N192
N
I
N
A
T
D
D
N
S
N
N
M
S
M
A
Red Bread Mold
Neurospora crassa
Q7SDP4
656
73993
M169
I
S
S
L
G
Q
T
M
P
P
Q
G
Q
Y
N
Conservation
Percent
Protein Identity:
100
99.8
99.7
74.4
N.A.
90.1
82.2
N.A.
80.8
78.3
58.4
68.2
N.A.
38.5
41.8
31.9
49.3
Protein Similarity:
100
100
99.8
74.7
N.A.
90.9
83
N.A.
86
84.1
64
75
N.A.
55.7
59.6
49.5
62.6
P-Site Identity:
100
100
100
93.3
N.A.
0
93.3
N.A.
6.6
93.3
6.6
0
N.A.
6.6
0
6.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
20
100
N.A.
13.3
100
40
6.6
N.A.
6.6
6.6
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
28
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.1
45.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
44
0
0
13
7
7
0
0
7
7
7
38
0
7
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
7
0
0
0
7
0
0
0
0
% D
% Glu:
7
0
0
0
7
0
0
0
0
0
0
7
0
7
13
% E
% Phe:
0
0
0
0
0
7
0
7
7
0
0
0
0
7
0
% F
% Gly:
0
7
7
13
19
0
7
7
7
7
0
7
0
0
7
% G
% His:
7
0
0
0
0
0
38
0
0
0
7
0
0
0
0
% H
% Ile:
13
7
0
0
0
0
0
0
7
0
7
0
0
0
7
% I
% Lys:
0
0
0
7
0
7
0
0
0
0
0
0
7
0
0
% K
% Leu:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
7
% L
% Met:
0
7
0
0
0
7
0
7
0
0
7
13
0
7
38
% M
% Asn:
7
7
13
0
0
0
0
13
0
44
7
0
13
7
7
% N
% Pro:
0
38
0
13
7
7
7
0
44
7
38
7
19
13
7
% P
% Gln:
0
7
13
7
0
7
0
7
7
7
7
7
7
7
0
% Q
% Arg:
7
0
50
38
44
0
13
19
7
0
0
0
7
0
0
% R
% Ser:
0
13
13
0
0
44
7
0
13
13
7
7
38
7
0
% S
% Thr:
13
13
7
0
13
13
19
38
0
7
7
13
7
7
7
% T
% Val:
7
7
0
7
0
0
0
0
0
7
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
7
7
7
7
0
7
38
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _